PATRICIA L. DORN

http://www.loyno.edu/~dorn/

Education/Degrees:

1989-1992 Post-doctoral Fellowship, Stanford University School of Medicine

1989 Ph.D., Molecular Biology and Virology, Zoology Dept., University of Maryland, College Park, MD

1980 B.A., Biology, University of California, San Diego, CA

Professional Positions:

2007-present Professor, Dept. of Biological Sciences, Loyola University New Orleans, LA

2000 - 2007 Associate Professor, Dept. of Biological Sciences, Loyola University New Orleans, LA

1994-2000 Assistant Professor, Dept. of Biological Sciences, Loyola University New Orleans, LA

2006-present  Adjunct Professor, Tulane University

2007- present  Adjunct Professor, School of Veterinary Medicine, Louisiana State University

2007- present Adjunct Professor, School of Public Health and Tropical Medicine, Tulane Health Sciences Center

1992-1994 Visiting Assistant Professor, Biology Dept., Hope College, Holland, MI

1989-1992 Postdoctoral Fellow in Molecular Parasitology with Dr. John C. Boothroyd, Stanford Medical School, Palo Alto, CA

Awards and Honors:

Dean’s Distinguished Teaching Professorship Jan. 2004 - Dec. 2006

Excellence in Research Award, College of Humanities and Natural Sciences 2007

Sigma Xi Member, 2009-present

Professional Affiliations:

  • Sigma Xi
  • American Society for Tropical Medicine and Hygiene
  • American Society for Microbiology   
  • Council for Undergraduate Research
  • Southeastern Society of Parasitologists

Extramural Grants:

5/1/2009-4/30/2012
National Institutes of Health, R15
Role: PI
“Taxonomy and Epidemiological Importance of Divergent Chagas Disease Vector Taxa”

1/1/2008-12/31/2009
Tulane University Health Sciences Center
Role: Co-Investigator, PI: Dr. Dawn Wesson
“Serosurvey for Human Exposure to Chagas Parasite in Southern Orleans Parish”

9/1/2007-7/31/2011
Board of Regents, Research Commercialization and Educational Enhancement,
Role: PI
“Chagas disease in southeastern Louisiana”

2002-2007
Role: Collaborator, PI: Dr. Frank Cogswell
National Institutes of Health, R01
“Survey of enzootic and arthropod vectors”.

Jan. 2001
Role: Co-author
Louisiana Board Of Regents
"A Proposal to the Louisiana Board Of Regents for Matching Funding for the Reverend John H. Mullahy, S.J., Eminent Scholar Chair In Environmental Biology"

8/1/1999-7/31/2002
Role: PI
National Institutes of Health, R15
"Genetic Structure of Chagas' Disease Vector in Guatemala”

7/1/95-6/30/96
Role: PI
American Heart Association, Beginning Grant-In-Aid
"Cloning virulence factors from Trypanosoma cruzi"

1989-1992
Individual National Institutes of Health Post-Doctoral Fellowship
Role: PI

Refereed Publications(*indicates undergraduate researcher):

Kroener, J.M., P.L. Dorn*, P.M. Shoor, I.G. Wickbom, and E.F. Bernstein. (1980) Prognosis of asymptomatic ulcerating carotid lesions. Archives of Surgery 115: 1387-92.

Derse, D., P.L. Dorn, L. Levy, R.M. Stephens, N. Rice, and J.W. Casey. (1987) Characterization of equine infectious anemia virus long terminal repeat. J. Virol. 61:743-7.

Dorn, P.L. and D. Derse. (1988) Cis and trans-acting regulation of gene expression of equine infectious anemia virus. J. Virol. 62:3522-6.

Dorn, P.L. , L. DaSilva, L. Martarano and D. Derse. (1990) Equine infectious anemia virus tat: Insights into the structure, function, and evolution of lentivirus trans-activator proteins. J. Virol. 64:1616-24.

Dorn, P.L. and J.C. Boothroyd. (1991) Inhibition of protein synthesis results in super-induction of procyclin (PARP) RNA levels. Mol. and Biochem. Parasitol. 44:133-140.

Evermann, J.F., D. Derse and P.L. Dorn. (1991) Interactions between herpesviruses and retroviruses: implications in the initiation of disease. Microbial Path. 10:1-9.

Dorn, PL , S Selgean*, M Guillot*. (1997) A simplified method for preservation and PCR amplification of Trypanosoma cruzi in human blood. Mem. Inst. Oswaldo Cruz 92:253-255.

Dorn, PL , D Engelke*, A Rodas, R Rosales, S Melgar, B Brahney*, J Flores*, and C Monroy. (1999) Utility of the Polymerase Chain Reaction in detection of Trypanosoma cruzi in Guatemalan Chagas vectors Am. J. Trop. Med. Hyg. 60: 740-745.

Dorn, PL , J Flores*, B Brahney*, A Gutierrez*, R Rosales, A Rodas, C Monroy. (2001) Comparison of Polymerase Chain Reaction on fresh tissue samples and fecal drops on filter paper for detection of Trypanosoma cruzi in Rhodnius prolixus. Mem. Inst. Oswaldo Cruz 96:503-505.

Dorn, PL , S Melgar, V Rouzier*, A Gutierrez*, C Combe*, R Rosales, A Rodas, S Kott*, D Salvia*, C. M. Monroy (2003)The Chagas Vector, Triatoma dimidiata (Hemiptera:Reduviidae), is Panmictic Within and Among Adjacent Villages in Guatemala. J. Med. Entomol. 40:436-440.

Calderón, C I; PL Dorn, S Melgar, J J Chávez, A Rodas, R Rosales, C M. Monroy. (2004) A preliminary assessment of genetic differentiation of Triatoma dimidiata, (Hemiptera: Reduviidae) in Guatemala by RAPD-PCR. J. Med. Entomol. 41:882 - 887)

Dorn, P, A Rodas, S Melgar, C Combe and C Monroy (2004) “Analysis of microsatellite markers for population genetic studies of the Chagas vector, Triatoma dimidiata”, Proceedings of the IX European Multicolloquium of Parasitology, Valencia, Spain, July 18-23, 2004.

Dorn, PL, C Monroy, A Curtis (2007) “T. dimidiata: A Review of its Diversity across its Geographic Range and the Relationship among Populations”, Infection, Genetics and Evolution, 7:343-352.

Dorn, PL, L Perniciaro*, MJ Yabsley, DM Roellig, G Balsamo, J Diaz, D Wesson (2007) “Autochthonous Transmission of Trypanosoma cruzi, Louisiana”, Emerging Infectious Diseases, 13: 605-607.

Melgar, S; JJ Chávez, P Landaverde, F Herrera, A Rodas, E Enríquez, P Dorn, C Monroy (2007) “Number of families of Triatoma dimidiata in a Guatemalan house” Mem Instituto Oswaldo Cruz, 102:221-223.

Dorn, P, P. Buekens, E. Hanford (2007) “Whac-a-mole: future trends in Chagas transmission and the importance of a global perspective on disease control” Future Microbology 2(4): 365-367 (Invited editorial).

S. S. Pineda, S. Melgar, P.  Dorn, E. Agreda, A. Rodas and C. Monroy (2008)
 “Salivary proteins profiles distinguish Triatomine species and populations of Triatoma dimidiata (Hemiptera: Reduviidae)”, J. Med. Entomol., 45(1): 52-58.

JK Blackburn, A Curtis, F Currin Mujica, F Jones, P Dorn, and R Coates (2008) “The Development of the Chagas’ Online Data Entry System (CODES-GIS)” Transactions in GIS 12(2):249-265.

P. L. Dorn, C. Calderon, S. Melgar, B. Moguel, E. Solorzano, E. Dumonteil, A. Rodas, N. de la Rua, R. Garnica, C. Monroy “Two distinct Triatoma dimidiata (Latreille, 1811) Taxa are Found in Sympatry in Guatemala and Mexico”. PLoS Negl Trop Dis 3(3): e393.

S. A. Klotz, P. L. Dorn, J.H. Klotz, J. L. Pinnas, C. Weirach, J. R. Kurtz, J. Schmidt
“Feeding behavior of Triatomines from the Southwestern United States: An Update on Potential Risk for Transmission of Chagas Disease”. Acta Tropica, 111(2):114-118.

Nieto PD, Boughton R, Dorn PL, Steurer F, Raychaudhuri S, Esfandiari J, Gonçalves E, Diaz J, Malone JB (2009). Comparison of two immunochromatographic assays and the indirect immunofluorscence antibody test for diagnosis of Trypanosoma cruzi infection in dogs in south central Louisiana.Vet Parasitol. 165 (2009) 241-7.

  1. Herrera-Aguilar, M., L. Be-Barragán, M. Ramirez-Sierra, F. Tripet, P.L. Dorn, and E. Dumonteil, Ph.D. Identification of a large hybrid zone between sympatric sibling species of Triatoma dimidiata in the Yucatan peninsula, Mexico, and its epidemiological importance. Infection, Genetics and Evolution 9 (2009) 1345-51.
  1. Klotz, J.H., Dorn, P.L., Logan, J.L., Stevens, L., Pinnas, J.L., Schmidt, J.O., and Klotz, S.A. “Kissing Bugs”: Potential Disease Vectors and Cause of Anaphylaxis”, Clin Infect Disease, 50 (2010) 1629-34.
  1. Stephen A. Klotz, Patricia Dorn, Justin O. Schmidt, and John H. Klotz “Kissing bugs are a household nightmare”, Pest Management Professional, 78 (2010) 49-52.
  1. de la Rua*, N., L. Stevens, P.L. Dorn. “High genetic diversity in a Triatoma sanguisuga population in New Orleans,” Infect Genet Evol. 11 (2011) 671-677.
  1. Dumonteil, E., F. Tripet, S. Gourbière, and P.L. Dorn. “Genetics and evolution of Triatomines: from phylogeny to vector control.” Invited review article for Heredity. In press
 
  1. Cesa, K., P. Dorn, K. Caillouët, D.Wesson. “High Trypanosoma cruzi Prevalence in Triatoma sanguisuga (Reduviidae: Triatominae) in Southeastern Louisiana,” J Med Entomol. (2011) (In press).
BOOK CHAPTERS AND MONOGRAPHS
  1. Monteiro, F., P. Marcet, and Dorn, P.L., Senior Author. “Chapter VIII: Population Genetics of Triatomines”. In American Trypanosomiasis Chagas Disease – One Hundred Years of Research (ISBN: 978-0-12-384876-5) edited by J. Telleria and M. Tibayrenc. (2010) 870pp.  Invited book chapter.
  1. Dorn, P.L., Senior Author, François Noireau, Elliot S. Krafsur, Gregory C. Lanzaro, and A. J. Cornel. “Chapter 18: ‘Genetics of Insect Vectors’”. Genetics and Evolution of Infectious Disease (ISBN: 978-0-12-384890-1), edited by Michel Tibayrenc, Editor-in-Chief. (2011) 772 pp. Invited book chapter.
  1. J.O. Schmidt, Stevens, L., Dorn, P., Mosbacher, M., Klotz, J., Klotz, S. “Kissing Bugs in the United States”. The Kansas School Naturalist. (ISBN0022-877X) 57 (2011) 15 pp. Monograph.
  1. Stevens, L., Dorn, P.L., Schmidt, J.O., Klotz, J.H., Lucero, D., Klotz, S.A. Kissing Bugs: The Vectors of Chagas. Adv. Parasitol. 75 (2011) 165-188. Invited book chapter.

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Courses Taught:

DNA and Societal Issues – Calif. Acad. of Sciences, San Francisco, CA.
Great Neglected Diseases of Humankind – Calif. Acad. Sci., San Francisco, CA. Biology of Parasitism (co-instructor) - Woods Hole, MA.
Principles of Biology Laboratory – Hope College, MI
Biology of Microorganisms, Lecture & Laboratory – Hope College, MI

Loyola University New Orleans
Cells and Heredity Biol A106
Cell and Molecular Biology, Lecture & Laboratory, Biol A206, A207
Genetics, Lecture & Laboratory, Biol A201, A202
Microbiology, Lecture & Laboratory, Biol A300, A301
Molecular, Cellular & Developmental Biology, Lecture & Laboratory, Biol A203
Molecular Genetics, Lecture & Laboratory Biol A394
Genetics & Society Biol Z138
Research Proposal Biol. A400
Independent Research Biol. A401
Research Thesis Biol. A402
Independent Study Biol. A499, A498

Tulane University
Microbiology

Student Mentoring:

I have been particularly interested in creating a stimulating environment for engaging undergraduates in biomedical research, especially students traditionally underrepresented in the sciences. Since joining Loyola in 1994, I have mentored thirty-four undergraduate students and six graduate students in original research in my lab. Of these undergraduate students, 75% were female, 47% minority (African-American or Hispanic) and 14% foreign students from countries where Chagas disease is a public health threat. I have directed honors theses for twenty-nine undergraduates working in my laboratory and fourteen additional undergraduate students working in other faculty labs. All of the research students mentored in my lab have advanced in biomedicine. The students have successfully competed for $38,706 in research funding.

Students mentored, funding obtained, projects, presentations and current positions:

Research presented at: 1Loyola Undergraduate Research Symposium, 2Beta Beta Beta regional meeting; 3Completed Senior Honors Thesis, 4SGA:Loyola Student Government Association funding.

Hope College:

  • Tuwanda Williamson (1993-1994) - "Molecular Diagnosis of Chagas Disease in Bolivia" (worked with PI in Bolivia, summer 1993) presented at: Hope College Summer Student Research Symposium, attended Medical School at the Univ. of Michigan, currently a physician, working in Bolivia.
  • Simona Selegean (1993-1994) - "Optimization of PCR detection of T. cruzi in vector samples"; graduated School of Optometry, Indiana University.

Loyola University New Orleans:

  • Nonhlanhla Majola 1,2,3 (1995-1996) - Council for Undergraduate Research grant (one of 45 nationwide),"Biological Characterization of T. cruzi strain SO 34, a major Bolivian Strain" presented at African Health Science Conference, Jan. 1997, South Africa, currently a laboratory supervisor in South Africa
  • Cao, Jeanette 1,2,3,4 (1995-1996) - "Possible interactions between T. cruzi and HIV"; Currently a dentist.
  • Daniel Salmeron (1996) "Possible interactions between T. cruzi and HIV"; graduated School at Tulane's School of Public Health and Tropical Medicine.
  • Monique Guillot 1,2,3,4 (1995-1997) Amer. Heart Assn. grant; "Detection of Trypanosoma cruzi in blood preserved in EDTA"; laboratory technician at the Mayo Clinic, currently a dentist.
  • Debra (Engelke) Mattis 1,2,3,4 (1996-1997), "Comparison of PCR and microscopy in the detection of T. cruzi in Guatemalan vectors"; currently a Physician's Assistant Anesthesiologist.
  • Bridget Brahney 1,2,3 (1996-1998) Am. Heart Assn. grant, Am. Soc. for Micro. grant (one of 23 nationwide) "Rates of infection of vectors with T. rangeli in Guatemala"; currently a dentist in New Orleans.
  • Juan Flores 1,2,3,4 (1997-1998) "Comparison of fresh tissue and filter paper samples in the detection of T. cruzi by PCR"; graduated Loyola Chicago Medical School.
  • Vanessa Rouzier 1,3,4 (1997-1998) Am. Heart Assn., SGA, "Population Genetics of Chagas disease Vectors in Guatemala", attending McGill Medical School, Canada (paper accepted for presentation at Am. Soc. for Trop. Med. meeting, Oct. 98, Puerto Rico, meeting cancelled). Currently a physician in Haiti.
  • Candice (Millro) 1,4 (1998-1999) "Population Genetics of Chagas Vectors"; graduated Xavier Pharmacy School, currently a pharmacist in Texas.
  • Robin DeVille 4 (1999) "Comparison of filter paper and fresh tissue samples for the detection of T. cruzi in vectors in Guatemala". Currently a forensic biologist.
  • Astrid Gutierrez 1,2,3,4 (1999-2001) "Genetic structure of Triatoma dimidiata within houses in Guatemala" 2nd place poster award at Tri-Beta meeting. Currently a physician in New York.
  • Sarah (Kott) Galfione 1,2,3,4 (1999-2001) "Genetic structure of Triatoma dimidiata in a village in Guatemala" 2nd place poster award at Tri-Beta meeting. Graduated Medical School Univ. of Texas Houston.
  • Crescent Combe 1,3 La. Indep. Colleges Found. grant, (2000-2002) "Genetic structure of Triatoma dimidiata among departments in Guatemala" Currently a graduate student at Tulane Health Sciences Center in neuroscience.
  • Debra Salvia (2000-2002) "Genetic structure of Triatoma dimidiata among departments in Guatemala" currently a Physician’s Assistant.
  • Miriam Ducruet 1,2,3,4 Weilbacher Found. grant, (2003-2004) “Population structure of Triatoma dimidiata across morphotectonic units in Central America and Mexico”. Currently in medical school in Guatemala.
  • Raquel Barrerra 1,3,4 (2003-2004) “Population structure of Triatoma dimidiata across morphotectonic units in Central America and Mexico” Currently in Tulane University Master’s program.
  • Megan Daigle 1,2,3,4 (2003-2005) SGA, Serological survey of primates at the Delta Primate center for Trypanosoma cruzi antibodies” Presentation at the Am. Soc. Tropical Med. & Hygiene meeting 12/2005 Wash, DC. Currently in LSU Medical School .
  • Juan Calix 1,2,3,4 (2004-2005) SGA, “Population structure of Triatoma dimidiata ”, travel award and presentation at the Am. Soc. Tropical Med. & Hygiene meeting 12/2005 Wash , DC. Currently in MD/PhD program at Univ. of Alabama.
  • Edson Gonçalves (2005) US-Brazil Higher Education Consortia Program, Fund for the Improvement of Postsecondary Education (FIPSE) “Prevalence of Trypanosoma cruzi in Dogs in the Atchafalaya Basin of Louisiana“ current: working at a veterinary clinical analysis lab (Brazil).
  • Ashley Tate1,3,4 (2005-2007) SGA $1793 “Strains of Trypanosoma cruzi circulating in Louisiana”, currently in graduate school at the University of Alabama.
  • Leon Perniciaro1,3 (2005-2007) “New microsatellite primers for population genetics of Triatoma dimidiata”, currently a laboratory technician in Pennsylvania.
  • Dr. Prixia Del Mar Nieto (2005-present) Veterinarian working on her Ph.D. at LSU Veterinary School “Environmental factors affecting Chagas disease in dogs in the Atchafalaya Basin of Louisiana”, current graduate student.
  • Paula Mischler (2006-present) “Chagas animal reservoirs in Louisiana” Ph.D. Student at LSU Veterinary School, current graduate student.
  • Kristina Cesa (2007) “Biology of Triatoma sanguisuga in SE Louisiana” Master’s student at Tulane School of Medicine, currently in Peace Corp in Honduras working on her MSc in International Health.
  • Fernanda M. de Carvalho (2007) US-Brazil Higher Education Consortia Program, Fund for the Improvement of Postsecondary Education (FIPSE) “Bloodmeal analysis of Chagas vectors in SE Louisiana”, returned to graduate studies in Brazil.
  • Lahra “Annie” Boitnot (summer 2007) Capstone project for her Master’s degree from Tulane Health Sciences Center “PCR detection of T. cruzi infection in non-human primates for Chagas vaccine study”.
  • Laurel Baul (2007-2008) Current student.
  • Mary Spulak (2007) Genetic structure of Triatoma sanguisuga in SE Louisiana. Currently in an MD/PhD program at Stanford University Medical School.
  • Jonathan Kurtz 1,3,4 (2007-present) “Chagas in the southern US” Currently a graduate student at Tulane University.
  • Poppy Markwell (2007-2008) Current graduate student at Tulane Health Sciences Center, Dr. Dawn Wesson, training in my laboratory.
  • Nick de la Rua 4 (2008-present) “Genetic structure of Triatoma dimidiata in Central America and Mexico” Current student
  • Daniel Pattillo (2008) “Control of Chagas disease in Guatemala”
  • Gabriela Estrada (2008-present) “Chagas vectors in SE Louisiana”, Current student.
  • Amanda Merlino (2008-2009), “Population subdivision of the main Chagas vector in Mesoamerica”, Currently a laboratory technician in Boston.
  • Jihan Shami (2009-present), “Taxonomy and Epidemiological Importance of Divergent Chagas Disease Vector Taxa”, Current student.

Contributions to the profession:

Reviewer for: BioMed Central, The American Journal of Tropical Medicine and Hygiene, Infection, Genetics and Evolution, Emerging Infectious Diseases, Annals of Tropical Medicine and Parasitology, Kinetoplastid Biology and Disease, Proceedings of the Royal Society: Biological Sciences, Vector-Borne and Zoonotic Diseases PLoS One, Journal of Parasitology, American Heart Association grant, book chapter for Text for Genetics, third Edition, published by WC Brown Publishers.

Technology Transfer:

Co-instructor in workshop presented at University of San Carlos, Guatemala entitled: "Entrenamiento tesrico-practico en tecnicas moleculares de PCR" (Theoretical & Practical training in PCR molecular techniques). July 2 - Aug. 2, 1999. 35 students from Guatemala and El Salvador participated.

Co-instructor in workshop presented at University of San Carlos, Guatemala entitled: "Generalidades de PCR-RAPDs para genética de poblaciones y producción de Taq polimerasa" (Use of RAPD-PCR for the study of population genetics and the production of Taq polymerase). July 10-13 th, 2000. 40 students in the lecture and 12 students in the laboratory from Guatemala and El Salvador.

Instructor for workshop on scientific writing at the University of San Carlos, Guatemala, summer 2002. Approximately 15 students from Guatemala participated.

Instructor for workshop on Active and Collaborative Learning at the University of San Carlos, Guatemala, summer 2005. Approximately 20 students and faculty participated.

Research

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Patricia Dorn, PhD,

Professor
Department of Biological Sciences
Loyola University New Orleans
6363 St. Charles Avenue
New Orleans, LA 70118
tel 504.865.3672
fax 504.865.2920
e-mail dorn@loyno.edu

Loyola University New Orleans
Department of Biological Sciences

last updated 8/14/2009

Copyright © 2001-2009 Dr. Patricia Dorn

The contents of this communication are the sole responsibility of Patricia Dorn and do not necessarily represent the opinions or policies of Loyola University New Orleans.